Huston’s scientists has discovered an easy way of losing a weight. Researchers found that perilipine, saving fats, is responsible for fat production. Covering a surface of fat drops, perilipine protects internal lipocytes from lipase, sensitive to hormones. This secures fats from processing, and fats are accumulated in an organism.

Fat maintenance process is disadvantageous for thin mice, because a lot of useful energy, which would be brought in with fats, is burnt out in it and useful substances are destroyed instead of fats. That’s why when mice are not hungry, perilipine generation process doesn’t go.

After intensive feeding of thin mice (they were given 25% more food), these mice have accumulated 8% of muscle mass and only a half of fats in excess of the fat they previously had. Being thin, mice don’t produce perilipine.

The purpose of the new anti-fat drug is to turn off the perilipine generation process. When the new anti-fat drug was given to mice genetically inclined to fatness, mice, having lost an ability to generate perilipine, became thin.

The results of the tests are very promising, since people have a similar process of fat accumulation. Success of the research can lay a foundation for creation of new anti-perilipine drugs intended to fight with a fatness.

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