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Scientific News    Health care    Preventive maintenance of diseases HIGH LEVEL OF CHOLESTERIN CONTENT IN BLOOD LIMITS ASPIRIN INFLUENCE EFFICIENCY

High level of cholesterin content in blood limits aspirin influence efficiency

A high level of cholesterin content in blood diminishes efficiency of aspirin influence. That was a conclusion of the Baltimore Medical center scientists. A daily dose of aspirin helps 75% of people suffering from cardial diseases to reduce a risk of infarct development; as for the rest 25% of patients, aspirin doesn’t help them at all. Now it was explained why some people consuming aspirin still remain unprotected. Scientists presented their research results at the 73rd Scientific Session of the American Heart Association held in New Orleans on November 14. Reports show that the remained 25% of patients had a high level of cholesterin which counteracted to efficient influence of aspirin on organism.

Aspirin swallowing thrombocyte accumulation lumps in blood vessels was recommended as an efficient drug for prophylactic against heart attacks development. In fact, however, 60% of patients with a cholesterin content of over 220 mg per decalitre still had thrombocyte accumulation in vessels despite they daily dosed aspirin during the treating course.

63 patients with a cardiovascular disease daily took 325 mg of aspirin within 30 days. Then their blood was examined to determine how blood thrombocytes clotted under aspirin effect. The test demonstrated that aspirin helped 41 patients to prevent thrombocyte adhesion; at the same time, 20 patients showed no response at all to aspirin effect. For a group of the patients with a high cholesterin content (over 220 mg per decalitre), aspirin didn’t help 60% of them at all. For a group of the patients with a cholesterin level below 180 mg per decalitre, aspirin didn’t give the expected result, i.e. it didn’t effect in full.

Therefore, people with an increased cholesterin content still remain in a high risk group, subjected to heart attacks.

Publishing date: November 23, 2000

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