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Scientific News    Health care    Cardiovascular diseases POLYCYSTOUS OVARY SYNDROME MIGHT RESULT IN WOMAN'S PREMATURE ATHEROSCLEROSIS

Polycystous ovary syndrome might result in woman’s premature atherosclerosis

Young women diagnosed with polycystous ovary syndrome (PCOS) have abnormalities related to ovary disfunction, which, in its turn, might lead to premature atherosclerosis in mean age. That were the results obtained by scientists of the University of Pittsburgh.

PCOS is one of the typical women’s reproductive organ disease: in the USA, 5% of women have such a disease. The disease is featured by a delay in menstrual cycle, sterility, high insulin level in a blood, and, very often, fatness.

Women suffering from PCOS are subjected to a high risk of getting atherosclerosis in mean age, even though they don’t have an overweight, hypertensia, and diabetes.

Despite the dangers stated above, PCOS very often remains unidentified in medical examinations at the early stage of its development. Gynecologists usually notice the abnormality when a menstrual cycle delays or sterility occurs.

Since PCOS might assist in developing atherosclerosis, women suffering from PCOS are in the largest group subjected to risk of cardiovascular disease development. That’s why it’s important for gynecologists to pay more attention to an issue of menstrual cycle delay to start treating the disease at the early stage.

Ultraechography of neck arteries of all participants of the survey (125 women suffering from PCOS, and 142 women who don’t have this disease) was carried out to assess the presence of a carotid spot or carotid swelling on artery walls, which are a sign of atherosclerosis. Theses abnormalities also allow to predict cardiovascular disease development.

It was found that the high risk group amounted to 21.6% of the PCOS-suffering women, as compared with 15.5% of the group healthy women were included in. It was also found that at 45 years the percentage of high-risky women group sharply grew in the PCOS-suffering group, while in the other group this share was practically unchanged. To obtain truly results, such factors as overweight, hypertensia, and diabetes, initiating atherosclerosis development, were excluded.

The National Institutes for Health supports the research. A sum of USD 1.7 bln will be channeled to assess the PCOS impact on women’s carotid atherosclerosis development over a 5-year term. The study is planned to begin in March, 2001, and will include application of a computer tomography.

Publishing date: November 16, 2000

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