Scientific News Health care Oncology HERPES-8 VIRUS IS A REASON OF KAPOSI'S SARCOMA DEVELOPMENT
Herpes-8
virus is a reason of Kaposi’s sarcoma development
Majority people usually don’t
think of a sexual way of spreading various infections: people only know about
such infection vehicles as AIDS and venereal diseases. Meanwhile, according to a
survey conducted at the University of Washington and Fred Hutchinson Cancer
Research Center in Seattle, human herpes-8 virus (HHV-8) initiating Kaposi’s
sarcoma could be transmitted during sexual acts.
Kaposi’s sarcoma is a tumor
typically produced in the form of purple spots on internal organs (abdominal
cavity and chest) and on a skin.
This kind of cancer has been
known over a century. Generally, people living in Southern Europe, the Middle
East and Africa were carriers of this disease. However, in the early 1980s
Kaposi’s sarcoma began penetrating to the USA and Western Europe. The
Kaposi’s sarcoma epidemic then started spreading among homosexuals, but
remained unnoticed on the background of AIDS, a new terrible sickness.
Kaposi’s sarcoma generally
develops in a human organism with a disordered immune protection capability.
That’s why the disease easily influences AIDS-diagnosed people.
This kind of cancer can
effectively be treated by means of chemotherapy which, unfortunately, sometimes
might induce metastases and lead to fatal consequences.
The HHV-8 was first discovered by
researchers of the University of Columbia in 1994. The HHV-8 is so far the
latest known “addition” to a generation of human herpes viruses which are
responsible for development of mouth and genital herpes, chickenpox and
infectious mononucleosis.
Despite the previously conducted
studies showed that in the USA the HHV-8 was more widely spread among people who
had frequent sexual contacts, the exact HHV-8 transfer mechanism remained
unclear. Besides, in Africa and Southern Europe the virus is transmitted via
another, non-sexual, way. Risks of falling ill with sarcoma are hierarchically
structured as follows:
- Sexual contacts with a person suffering from
Kaposi’s sarcoma
- Saliva exchange during kisses with a
HHV-carrier
- Use of amyl nitrite or inhalation of nitrites
(for this case, reliable information on getting ill with sarcoma is not
available).
An opinion that sarcoma development is on decline
is far from reality, since it’s based only on the available statistical
information which shows that percentage of people suffering from Kaposi’s
sarcoma goes down. These statistic data reflects a reduction in sarcoma sickness
rate of people who were identified as a HHV-8 carrier, in comparison with an
early stage of the AIDS epidemic in the early 1980s. This situation is likely to
have happened owing to a progress in treating AIDS-patients with drugs that
allowed to prevent further damage of human immune system.
Publishing date: November 14, 2000
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